PVAN Analysis Software

Pressure-Volume System

Millar's PVAN software provides a powerful, easy-to-use method for researchers to calculate the hemodynamic parameters of the pressure-volume (PV) data generated by the Millar Pressure Volume Systems and assess cardiac function.

Parameters Calculated by PVAN

PVAN opens the text files generated by the data acquisition software and applies a variety of algorithms to the PV data to calculate over 30 different hemodynamic parameters.

Parameters Calculated by PVAN Software
HR	Heart Rate	Ea	Arterial Elastance	dP/dt min	Minimum dP/dt
Vmax	Maximum Volume	CO	Cardiac Output	dV/dt max	Maximum dV/dt
Vmin	Minimum Volume	SW	Stroke Work	dV/dt min	Minimum dV/dt
Ves	End-Systolic Volume	SV	Stroke Volume	P@dP/dt max	Pressure at dP/dt Max
Ved	End-Diastolic Volume	EF	Ejection Fraction	P@dV/dt max	Pressure at dV/dt Max
Pmax	Maximum Pressure	PRSW	Preload Recruitable SW	V@dP/dt max	Volume at dP/dt Max
Pmin	Minimum Pressure	ESPVR	End-Systolic PV Relationship	V@dP/dt min	Volume at dP/dt Min
Pes	End-Systolic Pressure	EDPVR	End-Diastolic PV Relationship	Tau (Weiss)	Tau-Weiss Method
Ped	End-Diastolic Pressure	E(t)	Time Varying Max. Elastance	Tau (Glantz)	Tau-Glantz Method
Ees	End-Systolic Elastance	dP/dt max	Maximum dP/dt	Tau (Logistic)	Tau-Logistic Method

The calculated hemodynamic parameters serve as indicators of cardiovascular performance in response to different interventions (genetic mutations, drugs, occlusions, etc.). PVAN offers the researcher the opportunity to convert data to units of true volume, if the data is recorded RVUs.

PVAN Data Analysis Software

PVAN contains an intuitive user menu that offers easy access to a variety of displays and calculation tables for several cardiovascular parameters. A saline calibration feature allows the user to obtain a value for the parallel conductance volume contribution of the myocardium.

Pressure Volume Analysis Software

Integration with ADI Chart

PVAN allows seamless integrated access from ADInstruments Chart. Data can be recorded through Chart 5.4.2 and imported into PVAN by clicking the 'P' Heart icon in the Chart toolbar.

Pressure Volume Analysis

Data Export

Data may be easily exported to spreadsheets or text files, and graphical information can be placed into presentations or papers for publication.

Built-in Cuvette Calibration

PVAN 3.6 has an easy to use interface that calculates the volume calibration equation. Select the cuvette size and catheter, and then enter at least three sets of values into the well table. The slope and y-intercept values will be calculated and automatically entered into the volume calibration screen.