Telemetry Applications
Pressure - Measure high-fidelity arterial, left ventricular, ocular, uterine, venous and pleural pressure in animals > 200g
SNA - Measure high-fidelity sympathetic nerve activity in free-roaming conscious animals
Biopotential - Measure ECG, EMG, EEG or any voltage signal
Oxygen - Chronically monitor brain tissue oxygen in freely moving rats
TRM Telemetry System
The TRM telemetry system is the new standard in wireless, implantable telemetry technology to measure high-fidelity physiological signals in small animal models (> 200 grams), including high-fidelity pressure, sympathetic nerve activity (SNA), biopotentials (i.e., ECG, EMG, EEG) and tissue oxygen.
The small animal telemetry system offers researchers the ability to improve data quality in basic cardiovascular research, safety pharmacology studies and toxicology studies. Data can be recorded for longer periods of time and in conditions unhindered by anesthesia or restraint. Additional benefits include reduced handling induced stress artifact and lab maintenance.
The complete system requires the Telemeter, Configurator and SmartPad. Millar also recommends using ADInstruments PowerLab and Lab Chart Data Acquisition Hardware and Software for complete data analysis.
Telemetry System Benefits
- Replaces wires
- Enables long term recordings
- Enables monitoring in natural environments
- Reduces handling induced stress artifact
- Provides ability to use animals sequentially as their own controls or in multiple studies
- Provides round the clock measurements without lab personnel present
- Reduces the number of animals required
- Reduces animal maintenance costs
Advanced Telemetry Technology
Digital data transmission and wireless inductive power charging enable lifetime, 24/7 digital data from implanted telemeters in free-roaming conscious animals.
Traditional Telemetry vs. Telemetry Research
Traditional Telemetry |
Telemetry Research |
|
| Signals | Low fidelity pressure, temperature, activity, low frequency biopotential |
High-fidelity pressure, temperature, SNA, low and high frequency biopotential, tissue oxygen |
| Sampling Frequency | 250 to 500 Hz | Up to 8000 Hz |
| Transmission | All transmitters send data on a single frequency | Digital transmission offers multiple transmission bands |
| Animal size | Mice, rats and larger | Rats (>200 g) and larger |
| Recording range | Up to 1 m | Up to 5 m |
| Monitor duration | Limited by battery life | Unlimited - recharge in vivo |
| Continuous data | Limited by battery life | True 24/7 |
| Schedule data | Manual via magnet switch | Remote switch at receiver or via software |
| Refurbishment | Need to monitor battery state, refurbish when low |
No refurbishment waiting or cost, just recharge and continue |
| Co-housing/co-implants | Limited low frequency data from two animals | High frequency data from multiple animals |
| Output format | Proprietary interface | Standard analog voltage |
Telemetry Products
Telemeters
- Animals larger than 200 g (e.g., rats)
- Measures high-fidelity blood pressure, SNA (sympathetic nerve activity) and biopotentials (i.e., ECG, EMG, EEG)
- Wireless recharging in-vivo
- Transmission range up to 5 m
Hardware
- Configurator (TR190)
- SmartPad (TR180)
- PowerLab® Data Acquisition Systems
Accessories
- Surgical tools
- Training DVDs
- Practice transmitters
For more information on Millar blood pressure Telemetry Systems, call 832.667.7000 or complete our contact form.