Research and Papers

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Authors Title Journalsort icon Products Keywords Application Subject
Blanton R,
Takimoto E,
Aronovitz M,
Thoonen M,
Kass D,
Karas R,
Mendelsohn M
[] 		Mutation of the Protein Kinase I Alpha Leucine Zipper Domain Produces Hypertension and Progressive Left Ventricular Hypertrophy: A Novel Mouse Model of Age-Dependent Hypertensive Heart Disease
Link
 The Journals of Gerontology: Series A PVR-1045 left ventricular hypertrophy,
hypertension,
protein kinase G. 		Pressure-Volume Mouse
Chua J,
Zhou W,
Ho J,
Patel N,
Mackensen G,
Mahajan A
[] 		Acute Right Ventricular Pressure Overload Compromises Left Ventricular Function by Altering Septal Strain and Rotation
Link
 Journal of Applied Physiology 5F PV Loop Catheter,
3F PV Loop Catheter 		right ventricle,
cardiac function,
strain,
echocardiography 		Pressure-Volume Pig
Page B,
Young R,
Suzuki G,
Fallavollita J,
Canty J
[] 		The physiological significance of a coronary stenosis differentially affects contractility and mitochondrial function in viable chronically dysfunctional myocardium
Link
 Basic Research in Cardiology Millar Micromanometer hibernating myocardium,
stunned myocardium,
proteomics,
metabolism,
mitochondria 		Pressure Pig
Kavarana MN,
Loree HM,
Stewart RB,
Milbocker MT,
Hannan RL,
Pantalos GM,
Kung R
[] 		Pediatric Mechanical Support with an External Cardiac Compression Device
Link
 Journal of Cardiovascular Diseases & Diagnosis Dual transducer pressure catheter Pediatric mechanical support,
Congenital heart disease model 		Pressure Pig
Khan AR,
Majumder AAS,
Rahman MT,
Hoque
[] 		Increased Arterial Stiffness Correlates with the Severity of Coronary Artery Disease in Patients with acute ST Elevation MI
Link
 Cardiovascular Journal SPT-301 pulse wave analysis (PWA),
augmentation index (AIx),
arterial stiffness,
STEMI,
IHD 		Pressure Human
Babick A,
Elimban V,
Zieroth S,
Dhalla N
[] 		Reversal of Cardiac Dysfunction and Subcellular Alterations by Metoprolol in Heart Failure Due to Myocardial Infarction
Link
 Journal of Cellular Physiology SPR-249 congestive heart failure,
β-adrenoceptor blockers,
plasma catecholamines,
sarcoplasmic reticular Ca2+-pump,
myofibrillar ATPase 		Pressure Rat
Pendergrass K,
Boopathy A,
Seshadri G,
Maiellaro-Rafferty K,
Che P,
Brown M,
Davis M
[] 		Acute Preconditioning of Cardiac Progenitor Cells with Hydrogen Peroxide Enhances Angiogenic Pathways Following Ischemia-Reperfusion Injury
Link
 Stem Cells and Development MPVS Ultra Single Segment pressure-volume Pressure-Volume Rat
Williams A,
Hatzistergos K,
Addicott B,
McCall F,
Carvalho D,
Suncion V,
Morales A,
Da Silva J,
Sussman M,
Heldman A,
Hare J
[] 		Enhanced Effect of Combining Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and to Restore Cardiac Function After Myocardial Infarction
Link
 Circulation. 2013; 127: 213-223 MPVS Ultra Pressure-Volume System heart failure,
mesenchymal stem cells,
myocardial infarction,
stem cells 		Pressure-Volume Pig
Weltman N,
Wang D,
Redetzke R,
Gerdes A
[] 		Longstanding Hyperthyroidism Is Associated with Normal or Enhanced Intrinsic Cardiomyocyte Function despite Decline in Global Cardiac Function
Link
 PLoS ONE 7(10): e46655. doi:10.1371/journal.pone.0046655 Millar Mikro-Tip® pressure catheter Pressure Other Small Animal
Kutty, S,
Li L,
Padiyath A,
Nordmeyer S,
Gribben P,
Gao S,
Lof J,
Bidasee K,
Berger F,
Danford D,
Kuehne T
[] 		Real-time three-dimensional echocardiography integrated with diagnostic catheterization to derive left ventricular pressure–volume relations: a feasibility study
Link
 Eur Heart J Cardiovasc Imaging (2013) doi: 10.1093/ehjci/jes308 MPVS Ultra Pressure-Volume System three-dimensional echocardiography,
catheterization,
left ventricle,
pressure-volume relationship,
myocardial contractility 		Pressure-Volume Pig
Coquerel D,
Kusikova E,
Mulder P,
CoeffierM,
Renet S,
Dechelotte P,
Richard V,
Thuillez C,
Tamion F
[] 		Omega-3 Polyunsaturated Fatty Acids Delay the Progression of Endotoxic Shock-Induced Myocardial Dysfunction
Link
 Inflammation SPR-407 omega-3,
endotoxic shock,
myocardial dysfunction,
hemeoxygenase-1,
intestinal permeability,
TNF,
cytokine 		Pressure Rat
Wang L,
Yin J,
Nickles H,
Ranke H,
Tabuchi A,
Hoffman J,
Tabeling C,
Barbosa-Sicard E,
Chanson M,
Kwak B,
Shin H,
Wu S,
Isakson B,
Witzenrath,
de Wit C,
Fleming I,
Kuppe H,
Kuebler W
[] 		Hypoxic pulmonary vasoconstriction requires endothelial signal conduction via connexin 40
Link
 The Journal of Clinical Investigation SPR-1000 Pressure Mouse
Dai W,
Kearns-Jonker M,
Gerczuk P,
Gunthart M,
Girish N,
Pera M,
Mummery C,
Kloner RA
[] 		Abstract P028: The Effect of Cotransplantation of Human Embryonic Stem Cell--Derived Cardiomyocytes and Mesenchymal Stem Cells on Ventricular Function and Remodeling After Myocardial Infarction in Nude Rats
Link
 Circ Res. 2011; 109: AP028 Millar catheter myocardial infarction,
cells,
cardiac regeneration 		Pressure Rat
Kiyotake Ishikawa,
Elie R. Chemaly,
Lisa Tilemann,
Kenneth Fish,
Dennis Ladage,
Jaime Aguero,
Torsten Vahl,
Carlos Santos-Gallego,
Yoshiaki Kawase,
Roger J. Hajjar
[] 		Assessing left ventricular systolic dysfunction after myocardial infarction: are ejection fraction and dP/dtmax complementary or redundant?
Link
 J. Appl. Physiol. October 15, 2012 113:(8) 1267-1284 systolic dysfunction,
myocardial infarction,
strain imaging,
cardiac function 		Pressure-Volume Pig
Ye, Zeng-You,
Li, De-Pei,
Byun, Hee Sun,
Li, Li,
Pan, Hui-Lin
[] 		NKCC1 Upregulation Disrupts Chloride Homeostasis in the Hypothalamus and Increases Neuronal Activity–Sympathetic Drive in Hypertension
Link
 J Neurosci. 2012 Jun 20;32(25):8560-8. Millar Telemetry System Telemetry - Pressure Rat
Ye, Zeng-You,
Li, De-Pei,
Li, Li,
Pan, Hui-Lin
[] 		Protein Kinase CK2 Increases Glutamatergic Input in the Hypothalamus and Sympathetic Vasomotor Tone in Hypertension
Link
 J Neurosci. 2011 June 1; 31(22): 8271–8279. doi:10.1523/JNEUROSCI.1147-11.2011. Millar Telemetry System sympathetic nervous system,
essential hypertension,
synaptic transmission,
NMDA receptors,
hypothalamus 		Telemetry - Pressure Rat
Li, De-Pei,
Byan, Hee Sun,
Pan, Hui-Lin
[] 		Switch to Glutamate Receptor 2-Lacking AMPA Receptors Increases Neuronal Excitability in Hypothalamus and Sympathetic Drive in Hypertension
Link
 J Neurosci. 2012 Jan 4;32(1):372-80. Millar Telemetry System Telemetry - Pressure Rat
Zhang X,
Ga M,
Ha T,
Kalbfleisch JH,
Williams DL,
Li C,
Kao RL
[] 		The Toll-Like Receptor 9 Agonist, CpG-Oligodeoxynucleotide 1826, Ameliorates Cardiac Dysfunction After Trauma-Hemorrhage
Link
 Shock: August 2012 - Volume 38 - Issue 2 - p 146–152 doi: 10.1097/SHK.0b013e31825ce0de Pressure Mouse
Larauche M,
Mulak A,
Kim YS,
Labus J,
Million M,
Taché Y
[] 		Visceral analgesia induced by acute and repeated water avoidance stress in rats: sex difference in opioid involvement
Link
 Neurogastroenterology & Motility, DOI: 10.1111/j.1365-2982.2012.01980.x SPR-524 colorectal distension,
defecation,
estrous cycle,
manometry,
naloxone,
sex difference,
stress-related visceral analgesia,
water avoidance stress 		Pressure Rat
Uryash A,
Wu H,
Bassuk J,
Kurlansky P,
Adams JA
[] 		Preconditioning with periodic acceleration (pGz) provides second window of cardioprotection
Link
 Life Sciences, http://dx.doi.org/10.1016/j.lfs.2012.06.031 Millar Mikro-Tip® pressure catheter Preconditioning,
Nitric Oxide,
Myocardial infarction,
Endothelium-derived factors,
Second window of protection,
Cardioprotection,
Whole body periodic acceleration,
pGz 		Pressure Rat
Chan KYY,
Zhou L,
Xiang P,
Li K,
Cheung Ng PC,
Wang CC,
Li M,
Pong NH,
Tu L,
Deng H,
Kong CKL,
Sung RYT
[] 		Thrombopoietin improved ventricular function and regulated remodeling genes in a rat model of myocardial infarction
Link
 International Journal of Cardiology, http://dx.doi.org/10.1016/j.ijcard.2012.06.038 microtip pressure transducer catheter Thrombopoietin,
Myocardial infarction,
Microarray profiling,
Cardiac remodeling,
Endothelial progenitor cells 		Pressure Rat
Rubal BJ,
McKay K,
Armstrong KR,
Rubal MP,
Marbach MJ
[] 		Variability in intraosseous pressure induced by saline flush of an intraosseous cannula by multiple practitioners
Link
 Lab Anim (NY). 2012 Jul 20;41(8):224-9. doi: 10.1038/laban0812-224. Mikro-Tip SPC-781 intraosseous cannulation,
intraosseous pressure 		Pressure Pig
Srinivasan, V,
Nadkarni, V,
Yannopoulos, D,
Marino, B,
Sigurdsson, G,
McKnite, S,
Zook, M,
Benditt, D,
Lurie, K
[] 		Rapid Induction of Cerebral Hypothermia Is Enhanced With Active Compression-Decompression Plus Inspiratory Impedance Threshold Device Cardiopulmonary Resusitation in a Porcine Model of Cardiac Arrest
Link
 Journal of the American College of Cardiology, 47(4), pp.835–41. High-fidelity micromanometer-tipped catheter Intracranial Pressure,
Hemodynamics,
Induced Hypothermia,
Brain,
Cardiopulmonary Resuscitation 		IntraCranial Pressure Pig
Provenzano, P.,
Cuevas, C.,
Chang, A.,
Goel, V.,
Von Hoff, D.,
Hingorani, S.
[] 		Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
Link
 Cancer Cell 21, 418–429, March 20, 2012 SPR-1000,
PCU-2000 		IFP,
cancer 		Interstitial Fluid (Tumor) Pressure Mouse
Arindam Sen,
Maegan L. Capitano,
Joseph A. Spernyak, et al.
[] 		Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia, and enhances the efficacy of radiotherapy in murine tumor models
Link
 Cancer Res Published OnlineFirst April 21, 2011. SPR-524,
PCU-2000 		Tumor microcirculation and microenvironment,
Noninvasive imaging in "animal models",
Modification of radiation sensitivity,
Hyperthermia,
Hypoxia,
Interstitial fluid pressure,
Thermoregulation 		Interstitial Fluid (Tumor) Pressure Mouse
Gulliksrud, K,
Galappathi, K,
Rofstad, E
[] 		Interstitial Fluid Pressure and Vascularity of Intradermal and Intramuscular Human Tumor Xenografts
Link
 International Journal of Radiation Oncology * Biology * Physics - 1 May 2011 (Vol. 80, Issue 1, Pages 258-264, DOI: 10.1016/j.ijrobp.2010.11.042) Millar catheter Interstitial fluid pressure,
Blood perfusion,
Vascular morphology,
Transplantation site,
Dynamic contrast-enhanced magnetic resonance imaging 		Interstitial Fluid (Tumor) Pressure Mouse
Rofstad, E,
Gaustad, J,
Brurberg, K,
Mathiesen, B,
Galappathi, K,
Simonsen, T
[] 		Radiocurability Is Associated with Interstitial Fluid Pressure in Human Tumor Xenografts
Link
 Neoplasia. 2009 November; 11(11): 1243–1251. SPC-320 tumor pressure,
tumor IFP,
interstitial fluid pressure,
IFP,
transducer-tipped catheter Mikro-Tip SPC-320,
transducer Millar,
Power Lab 8/30 amplifier 		Interstitial Fluid (Tumor) Pressure Mouse
Simonsen, T,
Gaustad, J,
Leinaas, M,
Rofstad, E
[] 		High Interstitial Fluid Pressure Is Associated with Tumor-Line Specific Vascular Abnormalities in Human Melanoma Xenografts
Link
 Simonsen TG, Gaustad J-V, Leinaas MN, Rofstad EK (2012) High Interstitial Fluid Pressure Is Associated with Tumor-Line Specific Vascular Abnormalities in Human Melanoma Xenografts. PLoS ONE 7(6): e40006. doi:10.1371/journal.pone.0040006 SPC-320 (SPR-320),
TC-510 		high interstitial fluid pressure,
human melanoma xenografts 		Interstitial Fluid (Tumor) Pressure Mouse
Bates ML,
Fulmer BR,
Farrell ET,
Drezdon A,
Pegelow DF,
Conhaim RL,
Eldridge MW
[] 		Hypoxia recruits intrapulmonary arteriovenous pathways in intact rats but not isolated rat lungs
Link
 J Appl Physiol June 1, 2012 112:(11) 1915-1920; published ahead of print March 15, 2012, doi:10.1152/japplphysiol.00985.2011 MPVS Ultra,
SPR-839 		arteriovenous anastamose,
shypoxia,
intrapulmonary shunts,
lung,
microspheres 		Pressure-Volume Rat
Arai T,
Lee K,
Marini RP,
Cohen RJ
[] 		Estimation of changes in instantaneous aortic blood flow by the analysis of arterial blood pressure
Link
 J Appl Physiol June 1, 2012 112:(11) 1832-1838; published ahead of print March 22, 2012, doi:10.1152/japplphysiol.01565.2011 SPC-350 arterial blood pressure,
cardiac output,
stroke volume 		Pressure Pig