Designed for implantation periods over five years, TiSense is titanium-encapsulated, hermetically sealed, and set to revolutionize the industry.
TiSense is built for long-term use. Its titanium housing ensures durability, providing a solution for extended patient monitoring beyond traditional catheter-based sensors.
Using a MEMS piezoresistive sensor, TiSense delivers precise and consistent pressure measurements. This advanced technology provides exceptional sensitivity, ensuring seamless integration into medical devices for reliable chronic pressure monitoring.
The TiSense module features an absolute half-bridge sensor that measures pressure with respect to an internal vacuum, ensuring reliable pressure readings for long-term medical applications.
TiSense’s internal vacuum reference and external barometric sensor integration maintain precise pressure measurements, compensating for atmospheric pressure changes and ensuring exceptional accuracy throughout long-term use.
Suited for exposure to millions of pressure cycles, TiSense enables devices that can be placed at various points in the heart, offering readily available pressure data.
Paired with a shunt system, TiSense aids in managing CSF pressure to a desired value, enabling continuous measurement of intracranial pressure.
With a minimal height profile, TiSense is suited for long-term implantation in the inner eye, interfacing with a hermetic implant that houses signal conditioning electronics.
Beyond dynamic cardiovascular applications, TiSense is adaptable for use in static pressure settings, such as monitoring airway, spinal or compartment pressures. Its versatility allows for integration into a wide range of medical devices.
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TiSense is a MEMS piezoresistive sensor module filled with silicone oil, communicating pressure from a thin membrane in front. All body-contacting portions are constructed from titanium; the pins from the feedthrough are platinum-iridium. TiSense measuring system respects internal vacuum pressures.
Note: Care should be taken when soldering wires on pins to prevent heat damage. We recommend using a flex PCB to terminate the pins.
The long-term accuracy and stability of TiSense’s output over time has been assessed and quantified by an ongoing reliability drift test. TiSense is subjected to 80/120 mmHg sinusoidal-wave pressure cycles inside an environment filled with water at 37°C for simulating conditions within the human body. After every 20 million cycles (approximately one week), the pulsatile tester is stopped for collecting the drift data. The graph represents the drift over 13 weeks where TiSense was subjected to over 160 million pressure cycles, which is equivalent to 4 years of life in the human body.
| Parameter | Min | Typical | Max | Units | Notes |
|---|---|---|---|---|---|
| Operational Pressure Range | 510 | 1010 | mmHga | Range IS ±250 mmHg centered around atmospheric pressure (760 mmHGA). There can be ±15 mmHg variation in atmospheric pressure at the time of characterization. | |
| Accuracy Error | -0.5 | 0.5 | % (of applied pressure) | Includes errors from non-linearity over a range of 500 mmHg applied pressure. | |
| Warm-up Time | 1 | Hour | Final implanted temperature range. |
| Parameter | Min | Typical | Max | Units | Notes |
|---|---|---|---|---|---|
| Resistance | 2.2 | 3.2 | 4.2 | KΩ | Resistance of each sensing element as measured from C-A pin or C-P pin |
| Excitation Range | 1 | 6 | Volts DC | ||
| Sensitivity of Sensor | 10 | μV signal per volt of excitation per mmHg incident pressure. When completed with equivalent 3K resistors into a full bridge. |
| Parameter | Min | Typical | Max | Units | Notes |
|---|---|---|---|---|---|
| Height of Module | 1.57 | 1.7 | 1.83 | mm | Pin length not included |
| Diameter of Module | 3.87 | 4 | 4.13 | mm | |
| Material | Titanium Grade 2 | ||||
| Number of Pins | 3 |
| Parameter | Min | Typical | Max | Units | Notes |
|---|---|---|---|---|---|
| Operational Temperature Range | 35 | 37 | 39 | deg.C | |
| Storage Temperature Range | 20 | 40 | deg.C | Storage range until further testing is performed. |
TiSense is Millar’s fully integrated, biocompatible pressure sensor module, engineered for implantation periods greater than five years. Unlike traditional pressure sensors designed for acute use, TiSense features a MEMS piezoresistive sensing element housed in a hermetically sealed titanium enclosure, delivering exceptional reliability, long-term stability and seamless integration into a wide range of implantable medical devices.
TiSense is ideal for applications requiring long-term, implantable pressure measurement in medical devices. It is well-suited for chronic conditions such as heart failure, hydrocephalus and other in-vivo monitoring needs where durability, biocompatibility and signal stability are critical.
Interested in learning more about TiSense and its role in long-term pressure monitoring? Our medical applications team is here to answer your questions and help you explore how TiSense can support your clinical or research goals.
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Looking for detailed specifications on our TiSense module? Download the cutsheet to explore performance data, mechanical dimensions and more.