Millar's PVAN software provides a powerful, easy-to-use method for researchers to calculate the hemodynamic parameters of the pressure-volume (PV) data generated by the Millar Pressure Volume Systems and assess cardiac function.
PVAN opens the text files generated by the data acquisition software and applies a variety of algorithms to the PV data to calculate over 30 different hemodynamic parameters.
Parameters Calculated by PVAN Software
|HR||Heart Rate||Ea||Arterial Elastance||dP/dt min||Minimum dP/dt|
|Vmax||Maximum Volume||CO||Cardiac Output||dV/dt max||Maximum dV/dt|
|Vmin||Minimum Volume||SW||Stroke Work||dV/dt min||Minimum dV/dt|
|Ves||End-Systolic Volume||SV||Stroke Volume||P@dP/dt max||Pressure at dP/dt Max|
|Ved||End-Diastolic Volume||EF||Ejection Fraction||P@dV/dt max||Pressure at dV/dt Max|
|Pmax||Maximum Pressure||PRSW||Preload Recruitable SW||V@dP/dt max||Volume at dP/dt Max|
|Pmin||Minimum Pressure||ESPVR||End-Systolic PV Relationship||V@dP/dt min||Volume at dP/dt Min|
|Pes||End-Systolic Pressure||EDPVR||End-Diastolic PV Relationship||Tau (Weiss)||Tau-Weiss Method|
|Ped||End-Diastolic Pressure||E(t)||Time Varying Max. Elastance||Tau (Glantz)||Tau-Glantz Method|
|Ees||End-Systolic Elastance||dP/dt max||Maximum dP/dt||Tau (Logistic)||Tau-Logistic Method|
The calculated hemodynamic parameters serve as indicators of cardiovascular performance in response to different interventions (genetic mutations, drugs, occlusions, etc.). PVAN offers the researcher the opportunity to convert data to units of true volume, if the data is recorded RVUs.
PVAN contains an intuitive user menu that offers easy access to a variety of displays and calculation tables for several cardiovascular parameters. A saline calibration feature allows the user to obtain a value for the parallel conductance volume contribution of the myocardium.
PVAN allows seamless integrated access from ADInstruments Chart. Data can be recorded through Chart 5.4.2 and imported into PVAN by clicking the 'P' Heart icon in the Chart toolbar.
Data may be easily exported to spreadsheets or text files, and graphical information can be placed into presentations or papers for publication.
PVAN 3.6 has an easy to use interface that calculates the volume calibration equation. Select the cuvette size and catheter, and then enter at least three sets of values into the well table. The slope and y-intercept values will be calculated and automatically entered into the volume calibration screen.
For more information on PVAN pressure-volume analysis software or to request a quote, call 832.667.7000 or complete our contact form.