MPVS Ultra® Pressure Volume Loop System

Greater Insight in Every PV Loop

Comprehensive data leads to more powerful insights. That’s why Millar supports leading cardiovascular research efforts around the world with innovative instrumentation for complete pressure-volume (PV) loop analysis. With comprehensive data available at their fingertips in every application, researchers can make measurements, and decisions, with unprecedented accuracy, precision and confidence.

MPVS Ultra® Pressure-Volume Loop System

Millar’s MPVS Ultra® provides university labs, medical device organizations and pharmaceutical companies worldwide with robust, repeatable cardiovascular measurements to support a variety of research applications. Whether providing valuable cardiac function parameters in support of device validation or acting as a key component of a cardiovascular core research lab, the MPVS Ultra is ideally designed to meet the most advanced research needs.

Utilizing a market-first software controlled interface, the MPVS Ultra streamlines setup and calibration so that you can begin acquiring data as seamlessly as possible. The seven available volume segments, wide range of gain settings, integrated internal ECG circuit and dual pressure amplifiers allow comprehensive cardiac function assessment in a wide range of animal models.

The MPVS Ultra incorporates proven conductance technology and validated calibration methods to provide a variety of calibration options depending on your research needs. Whether you are collecting basic PV loop data for drug development or performing detailed analysis of a single hemodynamic parameter in support of a peer-reviewed publication, the MPVS Ultra system will deliver the performance you require.

Pressure-volume system features: Applications
  • Small and large animal
  • Dual pressure inputs
  • Seven volume segments plus composite volume
  • Internal ECG amplifiers
  • Software controlled user interface
  • Flexible gain and electrode configurations
  • Built-in volume calibration technique using Rho-cuvette
  • Comprehensive, easy-to-use analysis software
  • Compatible with Millar's single-segment and multi-segment Mikro-Tip® PV catheters
  • Baseline P-V loop analysis
  • Occlusion P-V loop analysis
  • Phenotyping gene manipulations
  • Cardiac hypertrophy
  • Cardiac failure
  • Cardiovascular remodeling
  • Toxicology
  • Pharmacology (rapid drug screening)
  • Cardiac resynchronization therapy
  • Surgical interventions
  • Ischemia/reperfusion studies


Millar recommends, provides and supports the ADInstruments PowerLab and LabChart Pro software for your complete PV data acquisition and analysis needs. The LabChart Pro software is a powerful yet simple to use software package that will provide real-time PV loop display and analysis along with additional comprehensive post-acquisition data analysis.

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For more information on these products or to purchase, call our exclusive distributor ADInstruments at 1 719.576.3970 or complete the form below.