The Mikro-Cath pressure catheter provides sleep disorder research specialists, pulmonologists and otolaryngologists with the ability to measure high-fidelity airway pressures in patients. The high-fidelity airway and esophageal pressure data supports understanding of respiratory physiology during obstructive sleep apnea and other apneic event studies.¹
Contact a Sales Rep or call 832-667-7000 to learn more about how the Mikro-Cath Pressure Catheter can advance your research.
The airway pressure application is approved for use in the United States. Pending CE Approval.
¹Ron Oliven, Guy Cohen, Yaniv Dotan, Mostafa Somri, Alan R. Schwartz, Arie Oliven, "Alteration in upper airway dilator muscle co-activation during sleep: comparison of patients with 4 OSA and healthy subjects.," American Physiological Society Journal, vol. 2017, 28 pages, 2017. doi:10.1152/japplphysiol.01067.2016
Airway pressure measurements support obstructive sleep apnea diagnosis through direct and reliable pressure readings in comparison to fluid-filled pressure measurements.
The human pharyngeal airway is collapsible and tends to obstruct above (OSA) or below 63 (healthy subjects) atmospheric pressure in the absence of active dilator muscle force¹. Intrathoracic pressure (Pes) was measured with a Millar catheter (Millar Inc. Houston, TX), positioned in the esophagus and used to measure the downstream pressure that developed during resistive breathing and during hypopneas and apneas. Analogue-to-digital acquisition of all parameters was performed at 1000 Hz for monitoring and data storage on a digital polygraphic data acquisition system (LabVIEW, National Instruments, Austin TX).
¹Oliven, Ron, et al. “Alteration in Upper Airway Dilator Muscle Co-Activation during Sleep: Comparison of Patients with OSA and Healthy Subjects.” Journal of Applied Physiology, 2017, doi:10.1152/japplphysiol.01067.2016.
Here are some other airway publications:
Chowdhuri, Susmita, et al. "Effect of Age on Long-Term Facilitation and Chemosensitivity during NREM Sleep." Journal of Applied Physiology, vol. 119, no. 10, 2015, pp. 1088–1096., doi:10.1152/japplphysiol.00030.2015. http://www.physiology.org/journal/jappl
Boudewyns, A.n., et al. “Site of Upper Airway Obstruction in Obstructive Apnoea and Influence of Sleep Stage.” European Respiratory Journal, vol. 10, no. 11, Jan. 1997, pp. 2566–2572., doi:10.1183/09031936.97.10112566. http://erj.ersjournals.com/
Oliven, Ron, et al. “Alteration in Upper Airway Dilator Muscle Co-Activation during Sleep: Comparison of Patients with OSA and Healthy Subjects.” Journal of Applied Physiology, 2017, doi:10.1152/japplphysiol.01067.2016. http://www.physiology.org/journal/jappl
Sands, Scott A, et al. "Quantifying the Arousal Threshold Using Polysomnography in Obstructive Sleep Apnea." Sleep, Sept. 2017, doi:10.1093/sleep/zsx183. https://academic.oup.com/sleep/advance-article-abstract/doi/10.1093/sleep/zsx183/4608578
Sankari, Abdulghani, et al. "Characteristics and Consequences of Non-Apneic Respiratory Events During Sleep." Sleep, Sept. 2016, doi:10.1093/sleep/zsw024. https://academic.oup.com/sleep/article-abstract/40/1/zsw024/2661543
El-Chami, Mohamad, et al. "Time of Day Affects the Frequency and Duration of Breathing Events and the Critical Closing Pressure during NREM Sleep in Participants with Sleep Apnea." Journal of Applied Physiology, vol. 119, no. 6, 2015, pp. 617–626., doi:10.1152/japplphysiol.00346.2015. http://www.physiology.org/journal/jappl
Wellman, A., et al. “Test of the Starling Resistor Model in the Human Upper Airway during Sleep.” Journal of Applied Physiology, vol. 117, no. 12, 2014, pp. 1478–1485., doi:10.1152/japplphysiol.00259.2014. http://www.physiology.org/journal/jappl
Can you confidently diagnosis sleep disorders with fluid-filled pressure measurement methods? Consider these differences between solid-state and fluid-filled pressure sensor technologies.
Mikro-Cath Solid-State Pressure Sensor Versus Traditional Fluid-Filled Pressure Measurements
|Accurate dP/dt||Unreliable dP/dt|
|True pressure signal||Augmentation of signal - overshoot, resonance|
|No time delay||Time delay|
|Free from motion artifacts||Motion artifacts - catheter whip|
|True pressure readings at any height in fluid||Gravitational effects on zero|
|WORKING LENGTH||120 cm|
|TIP F SIZE||3.5F|
|BODY F SIZE||2.3F|
|GUIDE CATHETER COMPATIBILITY||5F|
The Mikro-Cath Pressure Catheter is a single‐use catheter intended to be used for medical research and diagnostic purposes. The catheter is indicated to measure cardiovascular, intra-compartmental, and airway pressures in the human body. The catheter is used as a minimally invasive device under short-term limited body contact (<24 hours).
The Mikro-Cath may be introduced into the respiratory system through an existing orifice or through an incision.
Additional contraindications, precautions and warnings are referenced in the Instructions for Use available under the Knowledge Center acute catheter manuals.